Investors

Institutional Ownership

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 26 2.56 19.29 4,571,811
Mutual Fund 4 0.06 0.41 97,635
Insider 4 0.64 4.70 1,113,568

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 7 0.04 0.34 79,866
Sellers 11 -0.10 0.88 -208,729
Net -- -0.06 0.54 -128,863

Concentration

Value ($MM) % O/S Shares
Total Inst. 2.56 19.29 4,571,811
Top 10 Inst. 2.51 18.84 4,464,660
Top 20 Inst. 2.56 19.29 4,570,898
Top 50 Inst. 2.56 19.29 4,571,811

Style

Holders Value ($MM) % Inst Shares Shares
Growth 1 -- -- 2
Core Growth 1 -- -- 2
Index 4 0.03 0.29 69,208
Other 8 0.13 1.04 246,122
Broker Dealer 2 0.01 0.08 18,848
GARP 1 0.03 0.30 70,187
Hedge Fund 5 0.09 0.66 157,087
Value 1 -- -- 7
Core Value 1 -- -- 7

Location: Global Region

Holders % O/S Shares Share Change
North America 15 1.12 266,586 31,028
Europe 1 0.21 48,917 917

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Barberich (Timothy Joseph) 1,408,446 5.94 407,115 8/10/17
Wolfson (Alexey) 1,273,984 5.38 332,499 8/10/17
Eliseev (Alexey V) 950,312 4.01 -200,000 9/7/17
OPKO Health, Inc. 446,360 1.88 222,222 12/21/16
Cauwenbergh (Geert) 147,083 0.62 10,000 10/2/17
PanAgora Asset Management Inc. 70,187 0.30 -15,153 9/30/17
Two Sigma Investments, LP 59,258 0.25 26,889 9/30/17
Perinvest (UK) Ltd. 48,917 0.21 917 12/31/16
Millennium Management LLC 33,475 0.14 33,475 9/30/17
Geode Capital Management, L.L.C. 26,638 0.11 -- 9/30/17

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Perinvest (Lux) Sicav Global Healthcare Equity 48,917 0.21 917 12/31/16
Fidelity Extended Market Index Fund 26,638 0.11 -- 10/31/17
Vanguard Extended Market Index Fund 17,974 0.08 -- 10/31/17
iShares Core S&P Total U.S. Stock Market ETF 4,106 0.02 332 11/30/17

* Insider values reflect direct beneficial ownership.

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