Investors

Institutional Ownership

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 27 4.66 38.91 1,656,051
Mutual Fund 4 0.11 0.94 40,149
Insider 2 0.70 3.43 146,083

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 17 3.38 30.57 1,300,842
Sellers 9 -0.05 0.38 -16,286
Net -- 3.33 30.19 1,284,556

Concentration

Value ($MM) % O/S Shares
Total Inst. 4.66 38.91 1,656,051
Top 10 Inst. 4.40 37.08 1,578,100
Top 20 Inst. 4.66 38.89 1,655,062
Top 50 Inst. 4.66 38.91 1,656,051

Style

Holders Value ($MM) % Inst Shares Shares
Growth 1 0.03 0.23 10,000
Core Growth 1 0.03 0.23 10,000
Index 2 0.06 0.46 19,412
Other 6 2.07 18.84 801,772
Broker Dealer 3 0.13 0.98 41,576
Hedge Fund 3 1.94 17.86 760,196
Value 1 0.06 0.47 20,019
Deep Value 1 0.06 0.47 20,019

Location: Global Region

Holders % O/S Shares Share Change
North America 18 30.78 1,309,820 1,300,749
Europe 1 0.11 4,892 92

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Lincoln Park Capital 393,552 9.25 393,552 4/9/18
Sabby Management, LLC 377,652 8.87 377,652 4/9/18
Anson Funds Management LP. 377,652 8.87 377,652 4/9/18
Intracoastal Capital, L.L.C. 186,400 4.38 186,400 4/18/18
Eliseev (Alexey V) 95,031 2.23 13,250 9/7/17
OPKO Health, Inc. 44,635 1.05 -1 12/31/17
MYDA Advisors LLC 41,648 0.98 41,648 3/31/18
Virtu Americas LLC 20,824 0.49 18,283 3/31/18
Morgan Stanley & Co. LLC 20,687 0.49 20,687 3/31/18
First Allied Asset Management, Inc. 20,019 0.47 20,019 3/31/18

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Extended Market Index Fund 25,660 0.60 7,363 6/30/18
Fidelity Extended Market Index Fund 9,194 0.22 6,531 5/31/18
Perinvest (Lux) Sicav Global Healthcare Equity 4,892 0.11 92 12/31/16
iShares Core S&P Total U.S. Stock Market ETF 403 0.01 -- 6/30/18

* Insider values reflect direct beneficial ownership.

Copyright Thomson Reuters Corporation