Investors

Institutional Ownership

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 28 2.61 19.62 4,649,168
Mutual Fund 4 0.06 0.41 97,495
Insider 4 0.64 4.70 1,113,568

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 8 0.05 0.42 99,502
Sellers 9 -0.07 0.55 -131,372
Net -- -0.02 0.13 -31,870

Concentration

Value ($MM) % O/S Shares
Total Inst. 2.61 19.62 4,649,168
Top 10 Inst. 2.54 19.05 4,515,350
Top 20 Inst. 2.61 19.61 4,646,926
Top 50 Inst. 2.61 19.62 4,649,168

Style

Holders Value ($MM) % Inst Shares Shares
Growth 1 -- -- 2
Core Growth 1 -- -- 2
Index 4 0.03 0.29 69,208
Other 9 0.17 1.36 323,450
Broker Dealer 3 0.05 0.41 96,176
GARP 1 0.03 0.30 70,187
Hedge Fund 5 0.09 0.66 157,087
Value 1 -- -- 7
Core Value 1 -- -- 7

Location: Global Region

Holders % O/S Shares Share Change
North America 17 1.45 343,943 50,664
Europe 1 0.21 48,917 917

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Barberich (Timothy Joseph) 1,408,446 5.94 407,115 8/10/17
Wolfson (Alexey) 1,273,984 5.38 332,499 8/10/17
Eliseev (Alexey V) 950,312 4.01 -200,000 9/7/17
OPKO Health, Inc. 446,360 1.88 222,222 12/21/16
Cauwenbergh (Geert) 147,083 0.62 10,000 10/2/17
KCG Americas LLC 77,328 0.33 19,636 6/30/17
PanAgora Asset Management Inc. 70,187 0.30 -15,153 9/30/17
Two Sigma Investments, LP 59,258 0.25 26,889 9/30/17
Perinvest (UK) Ltd. 48,917 0.21 917 12/31/16
Millennium Management LLC 33,475 0.14 33,475 9/30/17

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Perinvest (Lux) Sicav Global Healthcare Equity 48,917 0.21 917 12/31/16
Fidelity Extended Market Index Fund 26,638 0.11 -- 9/30/17
Vanguard Extended Market Index Fund 17,974 0.08 -- 9/30/17
iShares Core S&P Total U.S. Stock Market ETF 3,966 0.02 192 10/31/17

* Insider values reflect direct beneficial ownership.

Copyright Thomson Reuters Corporation