Investors

Institutional Ownership

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 23 2.55 19.22 455,464
Mutual Fund 4 0.07 0.41 9,754
Insider 4 6.38 46.99 1,113,568

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 7 0.04 0.34 7,988
Sellers 8 -0.09 0.79 -18,675
Net -- -0.05 0.45 -10,687

Concentration

Value ($MM) % O/S Shares
Total Inst. 2.55 19.22 455,464
Top 10 Inst. 2.51 18.84 446,467
Top 20 Inst. 2.55 19.22 455,443
Top 50 Inst. 2.55 19.22 455,464

Style

Holders Value ($MM) % Inst Shares Shares
Index 4 0.03 0.29 6,920
Other 8 0.13 1.04 24,614
Broker Dealer 2 0.01 0.08 1,885
GARP 1 0.03 0.30 7,019
Hedge Fund 5 0.09 0.66 15,710
Value 1 -- -- 1
Core Value 1 -- -- 1

Location: Global Region

Holders % O/S Shares Share Change
North America 13 1.12 26,659 3,104
Europe 1 0.21 4,892 92

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Barberich (Timothy Joseph) 140,845 5.94 40,712 8/10/17
Wolfson (Alexey) 127,398 5.38 33,249 8/10/17
Eliseev (Alexey V) 95,031 4.01 -20,000 9/7/17
OPKO Health, Inc. 44,636 1.88 22,222 12/21/16
Cauwenbergh (Geert) 14,708 0.62 1,000 10/2/17
PanAgora Asset Management Inc. 7,019 0.30 -1,515 9/30/17
Two Sigma Investments, LP 5,926 0.25 2,689 9/30/17
Perinvest (UK) Ltd. 4,892 0.21 92 12/31/16
Millennium Management LLC 3,348 0.14 3,348 9/30/17
Geode Capital Management, L.L.C. 2,664 0.11 -- 9/30/17

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Perinvest (Lux) Sicav Global Healthcare Equity 4,892 0.21 92 12/31/16
Fidelity Extended Market Index Fund 2,664 0.11 -- 11/30/17
Vanguard Extended Market Index Fund 1,797 0.08 -- 11/30/17
iShares Core S&P Total U.S. Stock Market ETF 401 0.02 24 12/31/17

* Insider values reflect direct beneficial ownership.

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